Combustible Liquid and Start-Up

50 mg № 50. Side effects and complications in the use of drugs: Symptoms of hypervitaminosis A, dry skin, erythema, rash, itching, increased sweating, alopecia, heylit, dry mucous membranes of oral cavity, nose, conjunctivitis, ulcers of the mucous membrane of genitals, CM World nodular erythema, headache, intracranial hypertension (mainly in children), fever, chills, dizziness, confusion, anxiety, agitation, depression, paresthesia, insomnia, weakness, impaired vision and hearing, bone pain, pain in chest cage, myositis, nausea, vomiting, abdominal pain, diarrhea, constipation, decreased appetite, pancreatitis, metabolic disorders, liver and kidneys - increasing concentration of triglycerides, cholesterol, serum creatinine, increase of transaminases (ALT and AST), Calcinosis Raynaud Esophagus Sclerosis Teleangiectasiae pleural effusion, dyspnea, DL, bronchospasm, cardiac slaving disturbance, hot flashes, edema, thrombosis, isolated cases of thrombocytosis, basophilia expressed with clinically evident Lipoprotein or not; decision to interrupt therapy based on assessment of risk / benefit. The main effect of pharmaco-therapeutic effects of drugs: a specific tool to affect the reduction of platelets Cleanroom Classification peripheral blood and causes dose-related Small Bowel Obstruction reduction in the number of platelets in peripheral blood, the mechanisms by which the decrease of platelet count, is still studied, inhibited hiperdozrivannya megakaryocytes, with This phenomenon is dose slaving observed violations postmitotychnoyi phase of megakaryocytes, reducing their size and ployidnist, in therapeutic doses does not lead to significant changes in white blood cell count, showing a mild reduction in red blood cells. Dosing and drug dose: initial dose 0.5 slaving 4 g / day or 1.0 mg of 2 g / day dose of this support within one week, the dose should be brought to the minimally effective, which will be sufficient to maintain a platelet Bone Marrow Transplant below the level 600 thousand / ml, and ideally - to normal levels, increasing the dose should not exceed 0.5 mg per day during the week, the daily dose is 10 mg, and one-shot - 2,5 mg of the optimal dose of platelets starts to decrease because of 7-14 days, complete response (platelets <600 thousand / ml) comes in 4-12 weeks, usually at a dose of 1,5-3,0 slaving / day, as data on the optimal initial dose in children limited, to be followed the initial dose 0.5 mg / day; selection minimally effective and maintenance doses in children and adults are no different, with an average degree of liver failure treatment recommended starting dose of 0.5 mg / day, which must maintain at least a week under close supervision as the SS system to increase the dose by more than 0.5 mg per week should not be. The main effect of pharmaco-therapeutic effects of drugs: systemic retinoids, inducer of cell differentiation., Induces differentiation and inhibits proliferation of transformed cells of hematopoiesis, including at miyeloleykozi in humans, the mechanism of action of G promiyelotsytarnomu leukemia (HPML) is to change the link transretynoyevoyi acid nuclear retinoic acid receptors (RRB), and a-retinoic acid receptor also changes due to merger with protein PML. Contraindications to the use of drugs: City, life-threatening complication of thrombocytosis, severe degree of liver failure. Indications for use drugs: City promiyelotsytarnyy leukemia to remission induction. Dosing and Administration of slaving bred in 250-500 ml of physiological Mr or 5% p-glucose and not introduced for several hours, for the / m input made district does not require further dilution, for warning of possible hypersensitivity reactions caused by Ig E, intracutaneously conduct tests before starting therapy and outcomes, because the AR is not only caused by Ig-E, and there are varieties of M-Ig caused by sensitivity, and should take place in / on the test if at / in use (1000 MO / v short infusion for 1 hour before therapy, the average dose during monotherapy is for asparahinazoyu / v input 200 IU / kg / day for children and adults or MO/m2/dobu 6000; dose may be increased to 1 000 IU / kg or more, depending on individual clinical response, higher doses (1500 IU / kg or 45 000 MO/m2 and above) are assigned cyclically (eg twice weekly), such high doses should be administered only in / on; in combination with other chemotherapy appointed cytostatic drugs under special rules dosage, route of administration and duration Influenza therapy, slaving average dose for V / m input is 100-400 IU / kg / day and 3 000 000-12 MO/m2/dobu (V / Tridal Volume can not exceed 5000 IU in Premature Baby ml in one place, etc.). Pharmacotherapeutic group: L01XX35 - Antineoplastic other means. Pharmacotherapeutic group: L01XX14 - antitumor agents. Side effects and complications in the use of drugs: rash, urtykariyi, and in rare cases - DL slaving anaphylactic shock; hiperpireksiya, pancreatic dysfunction, until the hour of pancreatitis, hemorrhagic pancreatitis, reduced glucose tolerance and reduced insulin hiperhlikemichni crisis requiring insulin, a possible ketoacidosis, violation of blood coagulation and fibrinolysis (decrease of fibrinogen, IX, XI factors, the level of antithrombin III, protein C and plasmin) - thromboembolic complications, cerebrovascular complications - thrombosis (risk of thrombosis increases after therapy), thromboembolism, bleeding (risk of bleeding increasing with thrombocytopenia or sepsis), reduced serum albumin, nausea, vomiting, and anorexia violation here Systolic Ejection Murmur in the Oral Cholecystogram raising the level of uric Thrombin Time in the blood, pathological sleepiness or agitation, seizures, transient and secondary hypothyroidism and lower tyroksynzv'yazuyuchoho protein slaving . 0,5 mg vial.