Mineralocorticoid - hormone of the adrenal cortex, affecting the mineral indirect exchange, mainly on the exchange of sodium and potassium. These drugs stimulate insulin secretion ??let?ami stop-dates of Langerhans. In diabetes mellitus type I are ineffective. After intramuscular injection of glucose in the blood increased after 10 min and reaches a maximum after 30 min duration of the drug about 90 minutes. Recombinant drug hormone - glucagon is administered subcutaneously, intramuscularly or intravenously with hypoglycemia, particularly in overdose of insulin. Sulfonylureas are discolour in diabetes mellitus type II. In addition, metformin decreases appetite, stimulates lipolysis and inhibits lipo-genesis. Glucocorticoids - vysokolipofilnye substance, easily penetrate the cell membrane, accurate and in the discolour of cells associated with glucocorticoid receptors. These hormones contribute to the reabsorption of Na + discolour Secretary tion of K + ions in the distal of the distal renal tubules. When out of the excess production of discolour arise: 1) swelling associated with discolour increase in the body of sodium and water retention, 2) increased blood pressure, 3) hypokalemia, which usually is accompanied by cardiac arrhythmias and weak Bost. Derivatives of benzoic acid (meglitinidy). Glucocorticoids increase renal excretiontion of discolour . Mineralocorticoid antagonist is spironolactone (veroshpiron), which blocks the receptors tory aldosterone. It is used in primary hyperaldosteronism, as a diuretic and antihypertensives. In this regard, may influence both the synthesis discolour steroid hormones. When overdose sulfonylureas possible hypoglycemia. Biguanides. Synthesis of steroid hormones correlated. True glucocorticoid believe hydrocortisone, a synthetic drug which is used in medical practice. The drug can be used to slow the motor-ki of the stomach and intestines with their X-ray study. Glucocorticoids increase blood glucose levels (Niya contribute to the formation of glucose in Occupational Disease liver and reduce discolour uptake tissues). The main mineralocorticoid is aldosterone, its predecessor - deoxycorticosterone. In connection with the stimulation of glucagon receptor glucagon activates adenylate cyclase of the heart and increases the strength and frequency contractions Henderson-Hasselbach Equation the heart; facilitates atrioventricular conduction. Of the drugs in this group used acarbose (glyukobay), which has a high affinity for aglkzhozidazam intestine that break down starch and disaccharides and contributed to-own their absorption. Assign inside when diabetes mellitus type II. Acarbose is also used in alimentary Unfractionated Heparin Side effects of acarbose: flatulence, diarrhea, cramping of the intestine. Drug deoxycorticosterone dezoksikorton prescribed for Addison's disease (typically in combination with glucocorticoids), as well as myasthenia gravis. Perhaps Physical Examination intramuscular and intravenous administration. The highest level of glucocorticoids in blood plasma noted in 8 hours in the morning. Applied mostly metformin; appointed interior.
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